Compounded Semaglutide: How Many Units?
Compounded semaglutide comes in different strengths, so “0.25 mg” is a different number of units on every vial. Enter your concentration and dose to get the exact units to draw — and save your concentration so you never work it out again.
1. Your vial concentration
Printed on the vial or your pharmacy paperwork, in mg/mL (e.g. “5 mg/mL”).
2. Your prescribed dose
Read before you draw
- Use the concentration printed on your vial. Compounded semaglutide is made at different strengths, and using the wrong number causes a wrong dose.
- This assumes a standard U-100 insulin syringe (100 units = 1 mL). Confirm your syringe type.
- Always follow the exact instructions from your prescriber and compounding pharmacy — they override this tool.
- Compounded semaglutide is not an FDA-approved product. Double-check every dose; unit errors are a known cause of overdose.
Educational unit-conversion aid only — not medical advice, a prescription, or an endorsement of compounded semaglutide. Talk to a licensed clinician and your pharmacy about your dose.
The one formula behind it
Branded pens (Ozempic, Wegovy) dial your dose for you. A compounded vial doesn't — you draw the liquid yourself with an insulin syringe, so you need to turn milligrams (your dose) into units (the marks on the syringe).
units = (dose in mg ÷ concentration in mg/mL) × 100
because a U-100 insulin syringe holds 100 units per mL
Worked example: a 0.25 mg dose from a 5 mg/mL vial is 0.25 ÷ 5 = 0.05 mL, and 0.05 mL × 100 = 5 units. Change the concentration and the units change — that's exactly why using the number on your own vial matters.
A word on compounded semaglutide
Compounded semaglutide is not FDA-approved. Strength and quality vary by pharmacy, and drawing doses by hand introduces room for error — mg-to-unit mistakes are a documented cause of accidental overdose. Only use it under a licensed prescriber and pharmacy, follow their exact instructions, and double-check every dose. This page is an educational conversion aid, not advice to use compounded medication.
Frequently Asked Questions
Sources
- Wegovy (semaglutide) Prescribing Information — U.S. FDA (standard dose ladder)
- Compounding and the FDA: Questions and Answers — U.S. FDA (compounded drugs are not FDA-approved)
Tool Information
July 24, 2026
Dr. Jaydeep Sanghani
Meet Akabari
Dr. Jaydeep Sanghani
MBBS, MD, DNB(Anaesth.), PDCC(CCM), DrNB(CCM)
AIIMS Bhubaneswar · AIIMS Rishikesh
Critical care specialist and anesthesiologist with advanced training from AIIMS. Reviews health calculators at Calqulate to ensure medical accuracy and evidence-based standards.