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GLP-1 Hub

Stopping a GLP-1 & Maintaining Your Results

Losing weight is only half the treatment. The two calculators below cover the harder half: how to hold your loss on a maintenance dose, and what a taper or stop realistically looks like.

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Uses the published post-treatment data (STEP-4 for semaglutide, SURMOUNT-4 for tirzepatide) to model how much of your loss is typically regained after stopping, and how a taper changes the picture.

What the result means

The estimate is a trajectory based on trial averages. It helps you and your prescriber discuss whether now is the right moment to stop, and what a maintenance plan should look like.

Limitations

Regain depends heavily on nutrition, resistance training, sleep, and life stress — none of which the calculator can measure. The decision to stop, taper, or continue always belongs to your prescriber.

Open the stopping calculator

Educational tool, not medical advice.

Track your GLP-1 journey

Turn today's number into a real trajectory

Save every dose, weigh-in and symptom in one place. Nothing you enter is sold or shared.

Other GLP-1 hubs

Every other topic in the GLP-1 silo. One click to the section that fits where you are.

Tool Information

Last reviewed

August 2026

Reviewed by

Dr. Jaydeep Sanghani

Created by

Meet Akabari

Dr. Jaydeep Sanghani

Dr. Jaydeep Sanghani

MBBS, MD, DNB(Anaesth.), PDCC(CCM), DrNB(CCM)

AIIMS Bhubaneswar · AIIMS Rishikesh

Critical care specialist and anesthesiologist with advanced training from AIIMS. Reviews health calculators at Calqulate to ensure medical accuracy and evidence-based standards.

Educational only

Every tool and guide on this hub is written to help you understand your medication, not to prescribe it. All medical pages are reviewed by a licensed physician. Always confirm your dose, injection schedule and any symptom concerns with your own prescriber and pharmacist.